![]() In late 1981, cases began to be seen in injection drug users who were heterosexual, suggesting a pattern of infection that could be transmitted through blood. From the very beginning, investigators thought the problem was most likely due to an infectious agent that could be transmitted through sexual contact, although some speculated that recreational drugs or other environmental factors could also be causes. In response, CDC formed a Task Force on KS/OI in the summer of 1981. ![]() Health officials were alarmed that outbreaks of both PCP and KS, which were rare, deadly diseases associated with immune suppression, appeared in the same part of the population. ![]() After the report’s publication, health officials also noticed a spike in cases of Kaposi’s sarcoma (KS) external icon among gay men in New York. On June 5, 1981, CDC published a report in the MMWR describing requests for the drug pentamidine to treat a deadly disease called Pneumocystis carinii pneumonia (PCP) in five previously healthy young men in Los Angeles.
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